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Risk Factors

Capodanno D, Tamburino C.  Am Heart J 2011;161:462–70.

The SYNTAX (Synergy Between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery) score is a semiquantitative angiographic score that has been developed to prospectively characterize disease complexity in the coronary vasculature. In this article, the authors provide an overview of the background and currently available data on the use of the SYNTAX score in patients undergoing coronary revascularization as well as limitations of the score.

 

Risk stratification is essential for the optimal management of patients with ACS. Several risk scores have been developed and validated for use in ACS patients, and most of these have focused on a combination of clinical and readily available laboratory variables. The SYNTAX (Synergy Between Percutaneous Coronary Intervention [PCI] with Taxus and Cardiac Surgery) score is a semiquantitative angiographic score that is used to prospectively characterize disease complexity in the coronary vasculature. This score has been evaluated in various populations of patients, including those with coronary artery disease (CAD) undergoing either PCI or coronary artery bypass grafting (CABG). The calculations that are required in the SYNTAX score model are regarded by many as labor-intensive, and, in many cases, the results of validation studies of the model are somewhat conflicting. The authors of the present review article provide an overview of the currently available evidence on the use of the SYNTAX score in patients with multivessel or complex CAD, and discuss particular pitfalls and issues that are relevant to SYNTAX score application in clinical practice.

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