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Epidemiology of VTE

Enga KF, Brækkan SK, Hansen-Krone IJ et al.  J Thromb Haemost 2011;9:1334–9.

Alcohol consumption, types of alcoholic beverages and risk of venous thromboembolism - the Tromsø Study2

Hansen-Krone IJ, Brækkan SK, Enga KF et al.  Thromb Haemost 2011;106:272–8.

High-sensitivity C-reactive protein is not a risk factor for venous thromboembolism: the Tromsø study3

Hald EM, Brækkan SK, Mathiesen EB et al.  Haematologica 2011;96:1189–94.

These three studies report the findings of the Tromsø study, which sought to assess the risk of venous thromboembolism (VTE) associated with coffee consumption, alcohol consumption, and levels of high-sensitivity C-reactive protein in the general population. These findings indicate that moderate coffee consumption may be associated with a reduced risk of VTE, whereas scarce or frequent modes of consumption are associated with a higher risk. Furthermore, liquor consumption and binge drinking was associated with an increased risk of VTE, whereas wine consumption was possibly associated with reduced risk of VTE. Finally, a causal role for C-reactive protein in the pathogenesis of VTE was not observed.


Recently, the results of the Tromsø study – which assessed risk factors for venous thromboembolism (VTE) in the general population – were published. The Tromsø study was a single-center, prospective, population-based study, in which repeated health surveys of the inhabitants of Tromsø, Norway, were conducted. Participants were recruited from the fourth survey of the Tromsø Study (conducted in 1994–1995) and followed from the date of enrolment to the end of the study period (September 1, 2007).

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