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Volume 24 Issue 4

Paper of the Month

Estrogen receptor prevents p53-dependent apoptosis in breast cancer.

Bailey ST, Shin H, Westerling T et al.
Dana-Farber Cancer Institute, Boston, MA, USA.
Proc Natl Acad Sci U S A 2012;109:18060–5.
Breast tumors are characterized by extensive intertumoral genetic and clinical heterogeneity and a number of biological subtypes have been identified based on gene-expression profiles and, more recently, gene-expression profiles combined with DNA aberrations.
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