Predictors and outcome of low initial forced expiratory volume in 1 second measurement in children with cystic fibrosis.
Com G, Carroll JL, Castro MM et al.
University of Arkansas for Medical Sciences, Little Rock, AR, USA.
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J Pediatr 2014 Jan 10; Epub ahead of print.
In cystic fibrosis (CF), a poor clinical outcome has been shown to be closely linked to the presence of pulmonary infections, lung function measurements below normal values, and a poor nutritional status. Even in young individuals with CF, a poor nutritional status may be associated with a poor outcome several years later, and the development of chronic Pseudomonas aeruginosa lung infection with a mucoid phenotype can have a negative influence on survival.