Paper of the Month - December, 2011

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Propranolol for treatment of ulcerated infantile hemangiomas.

Saint-Jean M, Léauté-Labrèze C, Mazereeuw-Hautier J et al.
Propranolol was recently accepted as a treatment option for severe infantile hemangiomas (IH). Ulcerated hemangiomas pose an especially difficult challenge and can result in pain, infection, bleeding, and scarring, and interfere with feeding and sleeping. Treatment options for IH include systemic corticosteroids (Pediatrics 2009;124:423–31), intralesional corticosteroids, flashlamp pulsed-dye laser therapy, interferon-a, and vincristine. Complete wound healing can take up to 3 months with any treatment regimen (J Am Acad Dermatol 2001;44:962–72).


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