Paper of the Month - February, 2011

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Topical rapamycin: a novel approach to facial angiofibromas in tuberous sclerosis.

Haemel AK, O’Brian AL, Teng JM.
Facial angiofibromas (also known as adenoma sebaceum) are a cutaneous manifestation of tuberous sclerosis (TS). They can be relatively disfiguring and present a therapeutic challenge. This article is a case report of a 16-year-old girl with TS with both systemic and cutaneous involvement including progressive facial angiofibromas, gingival fibromas, renal angiolipomas, severe mental retardation, and epilepsy


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