Paper of the Month - August, 2013

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Myeloid marker S100A8⁄A9 and lymphocyte marker, soluble interleukin-2 receptor: biomarkers of hidradenitis suppurativa disease activity?

Wieland CW, Vogl T, Ordelman A et al.
Hidradenitis suppurativa (HS) is a chronic, recurring, inflammatory skin disease affecting the axillar, inguinal, and gluteal regions. Obesity and smoking seem to be risk factors for HS; however, the pathophysiology of HS is poorly understood. The longstanding inflammation of HS results in chronic scarring and the formation of sinus tracts or tunnels connecting abscesses in affected skin. Treatment of patients with HS is often difficult, and late-stage disease requires extensive surgery to improve the patients’ condition.