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Volume 29 Issue 4

Paper of the Month

Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1C targets.

De Vries JH, Bain SC, Rodbard HW et al.
Academic Medical Centre, Amsterdam, The Netherlands.
Diabetes Care 2012;35:1446–54.
Editor’s note: To date, there have only been trials of adding a glucagon-like peptide-1 (GLP-1) agonist to insulin therapy; no well-controlled trial has evaluated the addition of basal insulin to existing GLP-1 agonist therapy.
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