Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1C targets.
De Vries JH, Bain SC, Rodbard HW et al.
Academic Medical Centre, Amsterdam, The Netherlands.
» Read an expert review of this paper
Diabetes Care 2012;35:1446–54.
Editor’s note: To date, there have only been trials of adding a glucagon-like peptide-1 (GLP-1) agonist to insulin therapy; no well-controlled trial has evaluated the addition of basal insulin to existing GLP-1 agonist therapy.