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Hodgkin Lymphoma

Bohlius J, Schmidlin K, Boué F et al.; Collaboration of Observational HIV Epidemiological Research Europe.

University of Bern, Bern, Switzerland.

 Blood 2011;117:6100–8.

Editor’s note: Individuals infected with HIV have a risk of developing Hodgkin lymphoma (HL) that is up to 10-fold higher than that in HIV-negative persons. Although the advent of effective combination antiretroviral therapy (cART) has resulted in a substantial fall in the incidence of AIDS-defining cancers such as non-Hodgkin lymphoma (NHL) in HIV-positive individuals, this is not the case for HL; some studies in fact suggest an increased incidence. Furthermore, the relationship of absolute CD4+ cell count to HL risk remains unclear; published data are somewhat conflicting.

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