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Incorporating the New IASLC Staging System for Lung Cancer within 
Daily Practice 


Ramón Rami-Porta, MD1, and Peter Goldstraw, MB, FRCS2


The publication of the seventh edition of the tumor, node, metastasis (TNM) classification of lung cancer was the culmination of a dozen years of activities carried out by the International Staging Committee of the International Association for the Study of Lung Cancer (IASLC) [1]. The primary objective of the IASLC Lung Cancer Staging Project was to update and validate the TNM classification of lung cancer based on a large international database [2]. The proposed changes to the sixth edition of the TNM classification, derived from the analyses of this database, were published in peer-reviewed journals for public scrutiny and discussion [3–10], internally and externally validated [11], accepted by the International Union Against Cancer and the American Joint Committee on Cancer, and published as identical texts in those organizations’ respective staging manuals [12,13]. In addition to the new staging classification, much background material has been published by the IASLC in the first site-specific guidance on lung cancer: the IASLC Staging Manual in Thoracic Oncology [1].

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