0 rating

Deep Brain Stimulation for the Treatment of Epilepsy

Jyoti Pillai, MD1 and Michael R Sperling, MD2

Epilepsy is a chronic neurological disorder that is associated with significant rates of morbidity and mortality if seizures are uncontrolled. Despite the introduction of many new antiepileptic drugs, >30% of patients remain refractory to medical therapy [1]. Although some of these patients might have seizures that are amenable to epilepsy surgery, many are not candidates for surgical resection. Vagus nerve stimulation (VNS) can be considered in these patients. However, only 30–40% of patients with partial seizures report a response to VNS, which is nearly always palliative [2]. Alternative therapies need to be explored in these patients.

Return to top


Exosomes in Neurological Disease
Andrew F Hill
CML Neurology
Scans Without Evidence of Dopaminergic Deficit: Diagnosis, Etiology, and Management.
Timothy A Soane, PhD, Donald Grosset, MD, FRCP, Andrew J Lees, MD, FRCP, FMedSci, and Nin PS Bajaj, PhD,
CML Neurology
The Late Medical Complications of Severe Acquired Brain Injury in Children – Literature Review and Personal Practice. Part II: Non-Neurological Complications
Serena Haywood, MBBS, BSc, MRCP (Paed), MRCPCH, MSc1, Assunta Albanese, MD, FRCPCH, MPhil2, Ravi Chetan, MBBS, DCH, MRCP (Paed), MRCPCH2, Sonny Chong, FRCP (UK), FRCPCH, M. Med (Paed), MD3, and Paramala Santosh, MD, DipNB (Psych), FRCPsych, PhD4
CML Neurology
New Therapies for Treating Early Parkinson’s Disease
Zsigmond Tamás Kincses, MD, PhD, Nikoletta Szabó, MD, and Lászlo Vécsei, MD, PhD, DSc.
CML Neurology