Acute effects of aerosolized iloprost in COPD related pulmonary hypertension – a randomized controlled crossover trial.
Boeck L, Tamm M, Grendelmeier P et al.
University Hospital Basel, Basel, Switzerland.
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PLoS One 2012;7:e52248.
Editor’s note: The selective vasodilative properties of inhaled iloprost, a prostacyclin analogue, have previously been investigated in patients with interstitial lung disease, and the authors of an open-label study reported an improvement in 6-min walk distance (6MWD) in patients with chronic obstructive pulmonary disease (COPD) who received this agent (Respiration 2010;79:377–82).