Dual therapy in IPAH and SSc-PAH. A qualitative systematic review.
Johnson SR, Brode SK, Mielniczuk LM et al.
This article brings together in one place all of the data on combination therapy for pulmonary arterial hypertension (PAH) published to date. The heterogeneous nature of the data included (e.g. case reports to randomized controlled trials, upfront combination, add-on in stable patients, add-on in deteriorating patients, variable outcome measures) means that no robust conclusion can be drawn. Rather, this is a useful reference source.