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Management of Chronic Thromboembolic Pulmonary Hypertension

Stéphane Collaud, MD, MSc, and Marc de Perrot, MD, MSc

Pulmonary hypertension (PH) is defined as a mean pulmonary artery pressure (mPAP) of ≥25 mmHg at rest [1]. Based on differences in pathophysiological mechanism, clinical presentation, and therapeutic approach, PH is classified into five groups, with chronic thromboembolic PH (CTEPH) constituting group number 4 [2]. Group 4 used to be separated into proximal and distal CTEPH, but this distinction was removed in the last classification since both proximal and distal disease are potentially surgically accessible to pulmonary endarterectomy (PEA).

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