Robson J, Doll H, Suppiah R et al.
University of Oxford, Oxford, UK.
Ann Rheum Dis 2013 Nov 15; Epub ahead of print.
Lucía Silva’s review: In anti-neutrophil cytoplasmic antibody-associated vasculitides (AAV), the term damage refers to manifestations that cannot be reversed by an increase in therapy. The Vasculitis Damage Index (VDI) is a validated tool to record all damage since the onset of vasculitis, and is predictive of future mortality (Br J Rheumatol 1998;37:57–63, J Rheumatol 2010;37:374–8). The aim of the current observational study was to describe the type and extent of damage that occurred in AAV patients who were enrolled in six trials conducted by the European Vasculitis Study Group. A total of 735 AAV patients were included in the analysis. The mean age was 57.6 years and 43.3% of the patients were women. The mean follow-up was 87 months (7.3 years).