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Synthetic Mesh Augmentation for Pelvic Prolapse Repair

Alex Gomelsky, MD1, and Roger R Dmochowski, MD, FACS2

Recent studies estimate that pelvic organ prolapse (POP) and other pelvic floor disorders are increasingly common. A retrospective cohort study of all female members of the organization Kaiser Permanente Northwest (Portland, OR, USA), who underwent surgical treatment for prolapse and incontinence in 1995, estimated the lifetime risk of undergoing a single operation for prolapse or incontinence to be 11.1% by the age of 80 years, and that the number of prolapse surgeries in the US will exceed 250 000 annually [1]. Reoperation occurred in almost 30% of cases, and the time intervals between repeat procedures decreased with each successive repair. These findings are significant, as the proportion of women aged 65 years is expected to increase from 14.8% to 22.6% of the entire US female population between the years 2010 and 2050 [2]. Thus, the total number of women aged 65 years is expected to exceed 48 million by the year 2050. Since the population is aging and a significant number of women annually undergo surgery for POP, operations that optimize efficacy and minimize complications would be desirable. Unfortunately, recurrence rates are high, indicating that traditional approaches to POP repair that utilize native tissue may be suboptimal in many cases [1,3–6].

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