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Jull P, Risio LD, Horton C et al.

Royal Veterinary College, Hatfield, UK.

 Vet Rec 2011;169:361.

Editor’s note: This study explores the question of whether one seizure leads to another. In rat models, seizures that last for ≥30 min cause brain damage that results in epileptogenesis. Epileptogenesis refers to a process in which affected or damaged neurons form hyperexcitable, epileptic neuronal networks that trigger further seizures. In humans, prolonged febrile seizures in childhood have also been linked to the development of epilepsy in later life. However, no data have been published to confirm whether seizures beget seizures in veterinary patients.

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