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Editor’s note: Cystotomy is a common surgical procedure in small animal practice. Historically, inverting double-layer suture patterns have been recommended for cystotomy closure in dogs and cats, as these techniques are reported to create the best seal in the bladder wall and superior early wound strength. However, inverting suture patterns have been associated with complications such as delayed wound healing, with a prolonged inflammatory response and decreased urine capacity of the bladder.