Oblak ML, Boston SE, Geraldine Higginson G et al.
University of Guelph, Guelph, ON, Canada.
Vet Surg 2012;41(3):430–5.
Editor’s note: The current gold standard for the management of appendicular osteosarcoma (OSA) is amputation and adjuvant chemotherapy, which has a reported median survival time (MST) of 262–366 days. Limb-sparing procedures with adjuvant chemotherapy are also performed with the goal of curing the disease. Palliative treatment options for dogs with primary bone tumours include analgesia, radiotherapy, and primary surgical excision of the tumour without chemotherapy. In order to increase pain palliation, the addition of chemotherapy and pamidronate to these protocols has been advocated (Vet Clin North Am Small Anim Pract 2007;37:1091–110). The objective of this retrospective study was to compare the survival times associated with palliative radiotherapy alone and in combination with chemotherapy, pamidronate, or both in dogs with primary appendicular bone tumours. Fifty dogs with primary appendicular bone tumours were included in the study.