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Schilke HK, Sapienza JS.

Long Island Veterinary Specialists, Plainview, NY, USA.

 Vet Ophthalmol 2012;15:411–6.

James Oliver’s review: Keratoconjunctivitis sicca is a commonly diagnosed condition in dogs and is almost always a result of deficiency in the production of the aqueous component of the tear film. Immune-mediated destruction of lacrimal tissue is the most common cause of this condition, although congenital and neurogenic aetiologies are also encountered with reasonable frequency. Most cases of keratoconjunctivitis sicca can be successfully treated with topical immunomodulatory agents such as cyclosporine or tacrolimus, along with tear substitutes. Surgery is resorted to in those cases that do not respond to medical therapy; parotid duct transposition (PDT) is the surgical technique of choice. However, PDT is not without complications. The most frequent complications often relate to overproduction of saliva and associated mineral deposition on the ocular surface and eyelids. These, in turn, may be associated with blepharitis, facial dermatitis, and keratitis.

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