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Costenbader KH, Kang JH, Karlson EW. Am J Epidemiol 2010;172:205–16.

In this large cohort study, antioxidants did not appear to protect against the development of rheumatoid arthritis or systemic lupus erythematosus.


The Nurses Health Study cohorts have been a rich source of information on the epidemiology of autoimmune diseases in women, and more data continue to be gleaned from these US-based cohorts all the time. In this study, the authors examined the Nurses Health Study and the Nurses Health Study II to assess the potential role of antioxidants, which have been linked to systemic inflammation, in the prevention of both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).

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