Paper of the Month - February, 2011

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Computer tomography in pulmonary invasive aspergillosis in hematological patients with neutropenia: an useful tool for diagnosis and assessment of outcome in clinical trials

Caillot D, Latrabe VA, Thiébaut A et al.
In this study, the volume of pulmonary lesions on computed tomography scans was calculated in patients with invasive pulmonary aspergillosis at baseline and then sequentially during the course of antifungal therapy. Pulmonary lesions initially increased in size, then towards the end of therapy decreased to sizes similar to those seen at baseline. At the end of therapy, patients with a favorable response had smaller lesions compared with those with an unfavorable response.


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