Paper of the Month - November, 2011

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The diagnostic value of halo and reversed halo signs for invasive mold infections in compromised hosts

Georgiadou SP, Sipsas NV, Marom EM et al.
Observation of a halo or reverse halo sign on a computed tomography scan can be highly suggestive of early infection by an angioinvasive fungus; however, many other infectious and non-infectious etiologies are also associated with these signs. Although non-specific, both signs can provide sufficient evidence to prompt initiation of pre-emptive antifungal therapy in an immunocompromised patient.


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